Fatty acyl coenzyme A-sensitive adenine nucleotide transport in a reconstituted liposome system.

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Fatty acyl coenzyme A-sensitive adenine nucleotide transport in a reconstituted liposome system.

The adenine nucleotide translocase was purified from bovine heart mitochondria and incorporated into membranes of phospholipid liposomes. The rate of transport of the adenine nucleotides was competitively inhibited by oleoyl coenzyme A with an approximate Ki of 1.0 microM. Significant inhibition was limited to those fatty acyl coenzyme A esters which are carnitine dependent for their oxidation ...

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ژورنال

عنوان ژورنال: Journal of Biological Chemistry

سال: 1981

ISSN: 0021-9258

DOI: 10.1016/s0021-9258(18)43269-3